Hepatitis B
Hepatitis B is a disease that can be transmitted through sexual contact of semen (sexual transmitted disease / STD), blood or other body fluids. This disease can cause serious illness and lead to liver damage that can lead to death or liver cancer. Hepatitis B surface antigen consists of (surface antigen) is called the Australia antigen, since antigen was first found in Australia.
The incubation period of hepatitis B ranges between 45-180 days and the long incubation period depends on the amount of virus that enters the body and modes of transmission and patient endurance. The disease is often found in 30-50% in those aged> 50 years and 10% at age <50 years. Complaints on hepatitis B: nausea, loss of appetite, weakness, vomiting, pain in muscles and joints, fever, urinary dark brown and yellow skin. Most cases of hepatitis B infection will recover within 6 months and experienced immunity. In which 15-20% will become chronic hepatitis or chronic liver disease who later became the developing liver cirrhosis and liver cancer.
Hepatitis B virus (HBV) is a DNA virus that looks complex, has 2 layers of particles called Dane particles, the surface layer is called HBsAg and HBV in the core layer obtained hepatitis B core antigen (HbcAg). At the core of the viral genomes are circular DNA and double-stranded.
With the screening tests on blood transfusion, infection with hepatitis B disease is reduced by about 0.3 to 0.9% in patients receiving transfusions. The incidence of HBV infection high in: patients receiving repeated transfusions or blood components derived from multiple donors, patients with hemodialisi, drug addicts, puncture wounds circuitry Jarun syringes or other medical devices that have been contaminated, Acupuncture, tattoos, medical personnel, the transmission of mother-to-child and use a razor along patients with hepatitis B.
Infection with the hepatitis B virus can be cured spontaneously, subclinical infection to acute and fatal fulminant hepatitis (malignant)
To make a diagnosis of HBV can be used following parameters:
The incubation period of hepatitis B ranges between 45-180 days and the long incubation period depends on the amount of virus that enters the body and modes of transmission and patient endurance. The disease is often found in 30-50% in those aged> 50 years and 10% at age <50 years. Complaints on hepatitis B: nausea, loss of appetite, weakness, vomiting, pain in muscles and joints, fever, urinary dark brown and yellow skin. Most cases of hepatitis B infection will recover within 6 months and experienced immunity. In which 15-20% will become chronic hepatitis or chronic liver disease who later became the developing liver cirrhosis and liver cancer.
Hepatitis B virus (HBV) is a DNA virus that looks complex, has 2 layers of particles called Dane particles, the surface layer is called HBsAg and HBV in the core layer obtained hepatitis B core antigen (HbcAg). At the core of the viral genomes are circular DNA and double-stranded.
With the screening tests on blood transfusion, infection with hepatitis B disease is reduced by about 0.3 to 0.9% in patients receiving transfusions. The incidence of HBV infection high in: patients receiving repeated transfusions or blood components derived from multiple donors, patients with hemodialisi, drug addicts, puncture wounds circuitry Jarun syringes or other medical devices that have been contaminated, Acupuncture, tattoos, medical personnel, the transmission of mother-to-child and use a razor along patients with hepatitis B.
Infection with the hepatitis B virus can be cured spontaneously, subclinical infection to acute and fatal fulminant hepatitis (malignant)
To make a diagnosis of HBV can be used following parameters:
- Hepatitis B surface antigen (HBsAg)
- Hepatitis B e antigen (HBeAg)
- Hepatitis B e antibody (anti-HBe)
- Hepatitis B core antibody (anti-HBc) total
- Hepatitis B core antibody (anti-HBc IgM)
- Hepatitis B antibody (anti-HBs)
Complications of hepatitis B the most serious is death. Hepatitis B is one of the leading causes of death from liver failure akbat. And plus also of a study which shows hepatitis B are at risk for liver cancer occurs 200 times higher than those who do not suffer from hepatitis B.
In addition, some factors also play an active role in hepatitis B are:
The existence of some time or spontaneous episodes of hepatitis B who have problems exacerbations and also replication more leads in the direction of decompensation and liver disease progression in patients who had previously experienced a mild liver disease and also stable.
Mild form of this type of chronic persistent hepatitis, and at times will be transformed into a progressive then active chronic hepatitis and can also turn into liver cirrhosis.
In hepatitis B can act as a reservoir or as a source of infection in the area around the heart. Kortiosteroid are not able to perform the treatment in chronic hepatitis B, and in addition it is also a long time will cause a replica of hepatitis B and prevent the loss of HBeAg in the serum of the patient.
In the treatment of hepatitis B with interferon is to press and also to eliminate hepatitis B virus by simultaneously and comprehensively and can mengindusir recovery from heart disease and especially chronic hepatitis B is a disease. Below is the role of interferin for the treatment of hepatitis B is:
Helps to inhibit the replication of hepatitis B virus either through direct effects or also through stimulation of the immune system of patients with liver disease.
Helping menghentian or also inhibit necrosis of liver cells resulting from the occurrence of inflammatory reactions
Prevent the transformation of malignant cells in the liver.
Indication of the use of interferon are:
For patients with cases of HBV-DNA and HBeAg positive.
In patients with chronic active hepatitis disease that has been proven by histopathology.
And giving an indication of interferon can be considered by administration of interferon against acute fulminant hepatitis, although not many studies showing this field.
Side effects are usually generated from the use of interferon in hepatitis B are:
Early
General effects: fever over 40 derjaat centigrade, and the body feels cold chills, headache, anorexia, nausea, fatigue and muscle aches maximum sleeplessness and insomnia.
Effect rare: hiptensi, cyanosis, confusion, and changes in EEG
Slow approximately 2 weeks
General effects: fatigue, joint pain, drowsiness, weight loss, hair loss, emotional disturbance problems, bone marrow suppression.
Effect rare: agitation, depression, nausea, diarrhea, nasal hidun, sore throat, nephrotic syndrome.
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HOW I GOT MEDICATION
ReplyDeleteI thank Almighty God that human are not God, if not, by now i would have been a dead human, after so many years of been suffering for hepatitis B and all the Dr doctor said there is no cure, till this new year that i came in-contact with this clinic called MEDICATION CLINIC who deliver the medicine to me and now am cure.Am so thankful to God their email is healthmedlab@gmail.com